The Fly (1986)
Seth Brundle, a brilliant, but eccentric scientist attempts to woo investigative journalist Veronica Quaife by offering her the scoop on his latest research in the field of matter transportation. Brundle thinks he has ironed out all the problems with his process to transport a living creature, but when he attempts to teleport himself a fly enters one of the transmission booths, and Brundle finds he is a changed man. This Science-Gone-Mad film is the source of the quotable quote "Be afraid. Be very afraid."